The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2014
Filed:
Dec. 20, 2011
Piperazinone-substituted tetrahydro-carboline mch-1 antagonists, methods of making, and uses thereof
Applicants:
Matthew D. Surman, Albany, NY (US);
Peter R. Guzzo, Niskayuna, NY (US);
Inventors:
Matthew D. Surman, Albany, NY (US);
Peter R. Guzzo, Niskayuna, NY (US);
Assignee:
Albany Molecular Research, Inc., Albany, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); A61K 31/501 (2006.01); A61K 31/506 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention relates to piperazinone-substituted tetrahydrocarboline derivatives of formula (I): having the substituents as described herein which are melanin-concentrating hormone (MCH-1) receptor antagonists. The present invention also relates to pharmaceutical compositions including these compounds, and methods of preparation and use thereof.