The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2014

Filed:

Dec. 21, 2010
Applicants:

P. Jeffrey Conn, Brentwood, TN (US);

Craig W. Lindsley, Brentwood, TN (US);

Michael R. Wood, Brentwood, TN (US);

Rocco D. Gogliotti, Kingston Springs, TN (US);

Colleen M. Niswender, Brentwood, TN (US);

Bruce J. Melancon, Nashville, TN (US);

Evan P. Lebois, Atlanta, GA (US);

Inventors:

P. Jeffrey Conn, Brentwood, TN (US);

Craig W. Lindsley, Brentwood, TN (US);

Michael R. Wood, Brentwood, TN (US);

Rocco D. Gogliotti, Kingston Springs, TN (US);

Colleen M. Niswender, Brentwood, TN (US);

Bruce J. Melancon, Nashville, TN (US);

Evan P. Lebois, Atlanta, GA (US);

Assignee:

Vanderbilt University, Nashville, TN (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/08 (2006.01); A61K 31/439 (2006.01); A61K 31/4545 (2006.01); A61K 31/444 (2006.01); A61K 31/5377 (2006.01);
U.S. Cl.
CPC ...
Abstract

In one aspect, the invention relates to compounds having a general structure: which are useful as selective allosteric or bitopic agonists of the Mmuscarinic receptor; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds, for example, in treating neurodegenerative diseases, including Alzheimer's Disease. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.


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