The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2014

Filed:

Sep. 13, 2012
Applicants:

Gurdip Bhalay, Horsham, GB;

Emma Budd, Horsham, GB;

Graham Charles Bloomfield, Horsham, GB;

Stephen Paul Collingwood, Horsham, GB;

Andrew Dunstan, Horsham, GB;

Lee Edwards, Horsham, GB;

Peter Gedeck, Basel, CH;

Catherine Howsham, Horsham, GB;

Peter Hunt, Horsham, GB;

Thomas Anthony Hunt, Horsham, GB;

Paul Oakley, Horsham, GB;

Nichola Smith, Horsham, GB;

Inventors:

Gurdip Bhalay, Horsham, GB;

Emma Budd, Horsham, GB;

Graham Charles Bloomfield, Horsham, GB;

Stephen Paul Collingwood, Horsham, GB;

Andrew Dunstan, Horsham, GB;

Lee Edwards, Horsham, GB;

Peter Gedeck, Basel, CH;

Catherine Howsham, Horsham, GB;

Peter Hunt, Horsham, GB;

Thomas Anthony Hunt, Horsham, GB;

Paul Oakley, Horsham, GB;

Nichola Smith, Horsham, GB;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/62 (2006.01); A61K 31/55 (2006.01); A61K 31/4965 (2006.01); A61K 31/535 (2006.01); C07D 237/00 (2006.01); C07D 239/00 (2006.01); C07D 241/00 (2006.01); C07D 413/00 (2006.01); C07D 243/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

A compound of Formula I in free or salt or solvate form, where R, R, R, R, R, R, R, R, R, Rand Rhave the meanings as indicated in the specification, is useful for treating diseases which respond to the blockade of the epithelial sodium channel. Pharmaceutical compositions that contain the compounds and processes for preparing the compounds are also described.


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