The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2014
Filed:
Aug. 04, 2011
Geetanjali Chandrashekhar Chimote, Mumbai, IN;
Girish Badrinath Mahajan, Mumbai, IN;
Aravindan Vasudevan, Mumbai, IN;
Sivaramakrishnan Hariharan, Mumbai, IN;
Geetanjali Chandrashekhar Chimote, Mumbai, IN;
Girish Badrinath Mahajan, Mumbai, IN;
Aravindan Vasudevan, Mumbai, IN;
Sivaramakrishnan Hariharan, Mumbai, IN;
Priamal Enterprises Limited, Mumbai, IN;
Abstract
The present invention relates to a biodegradable, inhalable microparticle formulation comprising a compound of formula I obtained by fermentation of a microorganism of thespecies (PM0626271/MTCC5447), as described in PCT application publication WO2011027290, and a biodegradable lipid for drug delivery wherein the ratio of drug (compound of formula I) to lipid is 1:15 to 1:25. The present invention also relates to the process for preparation of the formulation and to the method of treatment of pulmonary tuberculosis, multi drug resistant tuberculosis (MDRTB), methicillin resistant(MRSA) pneumonias and methicillin sensitive(MSSA) pneumonias by administering therapeutically effective amount of the formulation to a mammal in need thereof. The present invention further relates to a method of delivering the microparticle formulation to a mammal in need thereof, wherein the formulation is administered by inhalation or intratracheal instillation for pulmonary delivery.