The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2014
Filed:
Oct. 20, 2010
Zhi-ren Liu, Atlanta, GA (US);
Jie Yang, Atlanta, GA (US);
Bing Xu, Atlanta, GA (US);
Wangda Zhou, Manchester, CT (US);
Shenghui Xue, Atlanta, GA (US);
Zhi-Ren Liu, Atlanta, GA (US);
Jie Yang, Atlanta, GA (US);
Bing Xu, Atlanta, GA (US);
Wangda Zhou, Manchester, CT (US);
Shenghui Xue, Atlanta, GA (US);
Georgia State University Research Foundation, Inc., Atlanta, GA (US);
Abstract
The 30 amino acid peptide GLP-1 has been integrated into the stable host protein human calbindin D9k. The fusion protein binds to GLP-1R. The fusion protein agents can be useful for both diabetes treatment and GLP-1R receptor targeting MR imaging. The fusion protein comprises a first peptide that selectively binds to a site of a target cell and linked to a second peptide, where the fusion protein is more stable than the first peptide alone and may further comprise a detectable label. The first peptide of the fusion protein may be glucagon-like peptide-1 (GLP-1), glucagon-like peptide-1 (GLP-1)(7-36), or glucagon-like peptide-1 (GLP-1) (9-36), or a conservative variant thereof.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile