The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2014
Filed:
Apr. 11, 2007
Donghui Huang, San Ramon, CA (US);
Charles M. Strom, San Clemente, CA (US);
Steven J. Potts, Flagstaff, CA (US);
Jenny Ellen Rooke, Seattle, WA (US);
Donghui Huang, San Ramon, CA (US);
Charles M. Strom, San Clemente, CA (US);
Steven J. Potts, Flagstaff, CA (US);
Jenny Ellen Rooke, Seattle, WA (US);
Quest Diagnostics Investments Incorporated, Wilmington, DE (US);
US Genomics, Inc., Woburn, MA (US);
Abstract
The present invention provides methods of determining the size of a particular nucleic acid segment of interest in a sample of nucleic acids through fragmentation of DNA, size fractionation, an optional second fragmentation, and identification using a marker sequence. In particular aspects, an expansion or reduction of tandem repeat sequences can be detected. In further aspects, carriers and individuals afflicted with fragile X syndrome or other diseases associated with tandem repeats can be distinguished from normal individuals.