The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2014
Filed:
Feb. 11, 2010
Akif Emre Tuereli, Saarbruecken, DE;
Bernd Penth, Lebach, DE;
Peter Langguth, Nieder-Olm, DE;
Bernd Baumstuemmler, Saarlouis, DE;
Akif Emre Tuereli, Saarbruecken, DE;
Bernd Penth, Lebach, DE;
Peter Langguth, Nieder-Olm, DE;
Bernd Baumstuemmler, Saarlouis, DE;
Instillo GmbH, Saarlouis, DE;
Abstract
Pharmaceutical drug particles of small particle size are produced by combining a solvent-non-solvent precipitate with an in-situ spray drying process. A pharmaceutical drug is dispersed in a water-miscible solvent, in particular ethanol, and heated in an infeed line under pressure to above the boiling point of the solvent until the drug dissolves. This solution collides as a fine liquid jet with a fine water jet in a gas-permeated microreactor, and the fine mist so arising vaporises rapidly. The organic solvent vaporizes first, then the water. The water may contain surface modifiers.