The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 15, 2014

Filed:

May. 27, 2008
Applicants:

Gale Smith, Rockville, MD (US);

Peter Pushko, Rockville, MD (US);

Kutub Mahmood, Rockville, MD (US);

Bin Zhao, Rockville, MD (US);

Inventors:

Gale Smith, Rockville, MD (US);

Peter Pushko, Rockville, MD (US);

Kutub Mahmood, Rockville, MD (US);

Bin Zhao, Rockville, MD (US);

Assignee:

Novavax, Inc., Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/145 (2006.01); C12N 15/44 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention discloses novel influenza virus-like particles (VLPs) that contain chimeric proteins or influenza membrane proteins. The chimeric proteins are derived from fragments of influenza membrane proteins fused to heterologous proteins. The invention includes antigenic formulations and vaccines comprising VLPs of the invention as well as methods of making and administering VLPs to vertebrates, including methods of inducing immunity to infections, such as influenza.


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