The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 15, 2014
Filed:
Nov. 06, 2006
Applicants:
Rino Rappuoli, Siena, IT;
Derek O'hagan, Siena, IT;
Giuseppe Del Giudice, Siena, IT;
Inventors:
Assignee:
Novartis AG, Basel, CH;
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/39 (2006.01); C12N 1/20 (2006.01);
U.S. Cl.
CPC ...
Abstract
Influenza vaccines containing insoluble particulate adjuvants have been found to elicit an IgG response that is primarily a TH2 response (IgG1). This response can be shifted towards a TH1 response (IgG2a) by including immunopotentiators in the compositions. Thus the invention provides an immunogenic composition comprising: (i) an influenza virus antigen; (ii) an insoluble particulate adjuvant; and (iii) a immunopotentiator.