The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2014

Filed:

Oct. 29, 2010
Applicants:

Jon Erik Braenden, Oslo, NO;

Aslak Godal, Oslo, NO;

Nils Olav Nilsen, Oslo, NO;

JO Klaveness, Oslo, NO;

Inventors:

Jon Erik Braenden, Oslo, NO;

Aslak Godal, Oslo, NO;

Nils Olav Nilsen, Oslo, NO;

Jo Klaveness, Oslo, NO;

Assignee:

Photocure ASA, Oslo, NO;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 229/00 (2006.01); A61K 31/195 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention provides an acid addition salt of 5-aminolevulinic acid (5-ALA) or of a 5-ALA derivative (e.g. a 5-ALA ester) with an acid which has a pKa of about 5 or less, preferably about 3 or less, with the proviso that the acid is other than hydrochloric acid. Particularly preferred salts are those derived from acids selected from the group comprising sulphonic acid and its derivatives, hydrobromic acid, sulfuric acid, nitric acid and phosphoric acid. The salts in accordance with the invention are particularly suitable for use as photosensitizing agents in diagnosis and photochemotherapy of disorders or abnormalities of external or internal surfaces of the body.


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