The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2014
Filed:
Mar. 24, 2011
Hyun Soon Lillehoj, West Friendship, MD (US);
Sung Hyen Lee, Laurel, MD (US);
Yeong Ho Hong, Geumjeong-dong Gunpo, KR;
Hyun Soon Lillehoj, West Friendship, MD (US);
Sung Hyen Lee, Laurel, MD (US);
Yeong ho Hong, Geumjeong-dong Gunpo, KR;
The United States of America, as represented by the Secretary of Agriculture, Washington, DC (US);
Abstract
NK-2 synthetic peptide derived from cationic core region of porcine NK-lysin has an antimicrobial and antitumor polypeptide that is considered to play a pivotal role in innate defense immunity. To evaluate the antimicrobial properties of synthetic chicken NK-lysin peptides, we investigated cytolytic activity against apicomplexan parasites likesporozoites,tachyzoites andsporozoites. The chicken NK-2 (cNK-2) lytic peptide which corresponds to amino acid residues of porcine NK-2 peptide significantly disruptedandsporozoites andtachyzoites. In contrast, no bactericidal activity was observed onBMH71-18. The cNK-2 lytic peptide is novel antimicrobial agent which can be used to intervene and treat economically costly infections in the animal industry.