The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2014

Filed:

May. 22, 2009
Applicants:

Brian K. Albrecht, Cambridge, MA (US);

Steven Bellon, Wellesley, MA (US);

Christiane M. Bode, Somerville, MA (US);

Alessandro Boezio, Somerville, MA (US);

Deborah Choquette, Medford, MA (US);

Jean-christophe Harmange, Andover, MA (US);

Inventors:

Brian K. Albrecht, Cambridge, MA (US);

Steven Bellon, Wellesley, MA (US);

Christiane M. Bode, Somerville, MA (US);

Alessandro Boezio, Somerville, MA (US);

Deborah Choquette, Medford, MA (US);

Jean-Christophe Harmange, Andover, MA (US);

Assignee:

Amgen Inc., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 519/00 (2006.01); A61K 31/437 (2006.01); A61K 31/4709 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Selected compounds are effective for prophylaxis and treatment of diseases, such as HGF mediated diseases. The invention encompasses novel compounds of Formula I, analogs, prodrugs and pharmaceutically acceptable salts thereof, pharmaceutical compositions and methods for prophylaxis and treatment of diseases and other maladies or conditions involving, cancer and the like. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.


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