The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2014
Filed:
Jul. 17, 2012
Esther A. Guzman, Fort Pierce, FL (US);
Jacob D. Johnson, Silver Spring, MD (US);
Amy E. Wright, Fort Pierce, FL (US);
Esther A. Guzman, Fort Pierce, FL (US);
Jacob D. Johnson, Silver Spring, MD (US);
Amy E. Wright, Fort Pierce, FL (US);
Florida Atlantic University Board of Trustees, Boca Raton, FL (US);
Abstract
Manzamine compounds have been discovered to decrease cell dissociation and cell migration associated with the metastatic potential of cancer cells and a restoration of cancer cell susceptibility to agents, such as TRAIL, which can induce apoptosis. Specifically, Manzamine A has a formerly unrecognized utility in both blocking tumor cell invasion and tumor metastasis as well in restoring cancer cell susceptibility to standard chemotherapeutic agents which induce apoptosis and, therefore, has utility in treating cancer.