The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2014
Filed:
Dec. 10, 2010
Feng Ling, Wako, JP;
Takehiko Shibata, Wako, JP;
Rong Niu, Tokyo, JP;
Minoru Yoshida, Tokyo, JP;
Yu-ichi Goto, Kodaira, JP;
Feng Ling, Wako, JP;
Takehiko Shibata, Wako, JP;
Rong Niu, Tokyo, JP;
Minoru Yoshida, Tokyo, JP;
Yu-ichi Goto, Kodaira, JP;
National Center or Neurology and Psychiatry, Tokyo, JP;
Riken, Saitama, JP;
Abstract
A method includes providing a eukaryotic cell including mutant mtDNA in which there is at least one mutation in the mtDNA, allowing the cell to come into contact with an active oxygen species or a chemical species that generates such an active oxygen species in the cell (e.g., hydrogen peroxide) and thereby changing the percentage of mutant mtDNA (mitochondrial genomic DNA) in the cell as a result of the contact. Also featured are cells obtained by the above-described method.