The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2014
Filed:
Nov. 26, 2010
Glenn Gaudette, Worcester, MA (US);
Matthew D. Phaneuf, Ashland, MA (US);
Syed Ali, Westborough, MA;
Brian Almeida, Cumberland, RI (US);
Helena Alfonzo, Chestnut Hill, MA (US);
Katie Flynn, Pawtucket, RI (US);
Glenn Gaudette, Worcester, MA (US);
Matthew D. Phaneuf, Ashland, MA (US);
Syed Ali, Westborough, MA;
Brian Almeida, Cumberland, RI (US);
Helena Alfonzo, Chestnut Hill, MA (US);
Katie Flynn, Pawtucket, RI (US);
Worcester Polytechnic Institute, Worcester, MA (US);
Abstract
The invention is directed to a device and method to prevent migration of Human Mesenchymal Stem Cells (hMSCs) from a delivery site while allowing communication between the stem cells and native cardiomyocytes. The device is characterized by scaffold pore size, fiber diameter and biomaterial selection. The invention includes a two part polyurethane scaffold that prevents migration of stem cells, allows gap junction formation through pores and is packaged for minimally invasive delivery.