The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 08, 2014
Filed:
Aug. 03, 2005
Applicants:
Frank Notka, Regensburg, DE;
Ralf Wagner, Regensburg, DE;
Diana Hammer, Regensburg, DE;
Inventors:
Assignee:
GeneArt AG, Regensburg, DE;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/10 (2006.01); C12N 7/01 (2006.01); C12N 15/00 (2006.01); C12N 15/33 (2006.01); A61K 48/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention relates to vector constructs for an HIV-specific gene therapy. The expression of transgenes is coupled with an infection of the cell with HIV while the transcription of the transgene is controlled by a transcription control region derived from HIV. In addition, the transgene is improved with regard to RNA stability and expression efficiency by modifying the nucleotide sequence.