The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 08, 2014

Filed:

Jan. 24, 2012
Applicants:

Shaomeng Wang, Saline, MI (US);

Haibin Zhou, Ann Arbor, MI (US);

Jianfang Chen, Ann Arbor, MI (US);

Angelo Aguilar, Ann Arbor, MI (US);

Jennifer L. Meagher, Plymouth, MI (US);

Duxin Sun, Ann Arbor, MI (US);

Chao-yie Yang, Ann Arbor, MI (US);

Liu Liu, Ann Arbor, MI (US);

Longchuan Bai, Ann Arbor, MI (US);

Donna Mceachem, Ann Arbor, MI (US);

Jeanne Stuckey, Fenton, MI (US);

Xiaoqin LI, Ann Arbor, MI (US);

Inventors:

Shaomeng Wang, Saline, MI (US);

Haibin Zhou, Ann Arbor, MI (US);

Jianfang Chen, Ann Arbor, MI (US);

Angelo Aguilar, Ann Arbor, MI (US);

Jennifer L. Meagher, Plymouth, MI (US);

Duxin Sun, Ann Arbor, MI (US);

Chao-Yie Yang, Ann Arbor, MI (US);

Liu Liu, Ann Arbor, MI (US);

Longchuan Bai, Ann Arbor, MI (US);

Donna McEachem, Ann Arbor, MI (US);

Jeanne Stuckey, Fenton, MI (US);

Xiaoqin Li, Ann Arbor, MI (US);

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 51/00 (2006.01); A61K 31/5377 (2006.01); A61K 31/496 (2006.01); C07D 413/14 (2006.01); C07D 403/12 (2006.01); C07D 401/14 (2006.01); C07D 403/10 (2006.01); C07D 405/10 (2006.01); A61P 35/00 (2006.01); A61K 31/5513 (2006.01); C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

Inhibitors of Bcl-2/Bcl-xL and compositions containing the same are disclosed. Methods of using the Bcl-2/Bcl-xL inhibitors in the treatment of diseases and conditions wherein inhibition of Bcl-2/Bcl-xL provides a benefit, like cancers, also are disclosed.


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