The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Sep. 08, 2010
Tero Kunnari, Aschaffenburg, DE;
Holger Bindernagel, Gelnhausen, DE;
Sascha Weiser, Maintal, DE;
Andrew Lupton, Gelnhausen, DE;
Stefan Wallert, Seligenstadt, DE;
Tero Kunnari, Aschaffenburg, DE;
Holger Bindernagel, Gelnhausen, DE;
Sascha Weiser, Maintal, DE;
Andrew Lupton, Gelnhausen, DE;
Stefan Wallert, Seligenstadt, DE;
Heraeus Precious Metals GmbH & Co. KG, Hanau, DE;
Abstract
4'-epidaunorubicin hydrochloride is provided in a crystalline form which is stable and readily soluble. A process of producing the crystalline form includes crystallizing 4′-epidaunorubicin hydrochloride in a solvent system including (a) solvent A selected from Cand Chalogenated solvents and mixtures thereof, (b) solvent B selected from C-Cstraight and branched alcohols and mixtures thereof, and (c) solvent C selected from C-Cstraight and branched alcohols and mixtures thereof, wherein solvent C is selected to provide lower solubility to 4′-epidaunorubicin hydrochloride than solvent B.