The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Jul. 13, 2012
Applicants:
Mark S. Cushman, West Lafayette, IN (US);
Evgeny A. Kiselev, West Lafayette, IN (US);
Andrew E. Morrell, San Diego, CA (US);
Inventors:
Mark S. Cushman, West Lafayette, IN (US);
Evgeny A. Kiselev, West Lafayette, IN (US);
Andrew E. Morrell, San Diego, CA (US);
Assignee:
Purdue Research Foundation, West Lafayette, IN (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 471/00 (2006.01); C07D 221/22 (2006.01); A61K 31/44 (2006.01);
U.S. Cl.
CPC ...
Abstract
The invention described herein pertains to substituted azaindenoisoquinoline compounds, in particular 7-, 8-, 9-, and 10-azaindenoisoquinoline compounds, which are inhibitors of topoisomerase I, processes and intermediates for their syntheses, pharmaceutical compositions of the compounds, and methods of using them in the treatment of cancer.