The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Sep. 16, 2010
Eelco Ruijter, Woerden, NL;
Romano Orru, Haarlem, NL;
Anass Znabet, Amsterdam, NL;
Marloes Polak, Voorhout, NL;
Nicholas Turner, Manchester, GB;
Eelco Ruijter, Woerden, NL;
Romano Orru, Haarlem, NL;
Anass Znabet, Amsterdam, NL;
Marloes Polak, Voorhout, NL;
Nicholas Turner, Manchester, GB;
Abstract
The present invention relates to a process for the preparation of a compound of the general Formula (I), comprising: a) reacting a compound of the general Formula (II) with a compound of the Formula III RCOOH and a compound of the general Formula IV RNC under such conditions that compound I is formed, wherein Rrepresents a substituted or unsubstituted alkyl, alkenyl, alkynyl, aromatic or non-aromatic, mono-, di- or tricyclic, or heterocyclic structure, and Rrepresents a substituted or unsubstituted alkyl, alkenyl, alkynyl, aromatic or non-aromatic, mono-, di- or tricyclic, or heterocyclic structure, and Rrepresents a substituted or unsubstituted alkyl, alkenyl, or alkynyl structure. In further aspect the subject invention relates to the use of the obtained products as intermediates for various peptidomimetics, and preferably as a building block in a convergent synthesis of prolyl dipeptide structures.