The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Jan. 14, 2010
Applicants:
Christopher Bieniarz, Tucson, AZ (US);
Julia Ashworth-sharpe, Tucson, AZ (US);
Casey A. Kernag, Tucson, AZ (US);
Jerome W. Kosmeder, Tucson, AZ (US);
Mark Lefever, Tucson, AZ (US);
Inventors:
Christopher Bieniarz, Tucson, AZ (US);
Julia Ashworth-Sharpe, Tucson, AZ (US);
Casey A. Kernag, Tucson, AZ (US);
Jerome W. Kosmeder, Tucson, AZ (US);
Mark Lefever, Tucson, AZ (US);
Assignee:
Ventana Medical Systems, Inc., Tucson, AZ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 1/13 (2006.01); C07K 1/10 (2006.01); G01N 33/532 (2006.01);
U.S. Cl.
CPC ...
Abstract
A method is disclosed for making a conjugate of two molecules using a hydrazide thiol linker. In a particular working embodiment, an Fc-specific antibody-enzyme conjugate is made using the method and demonstrated to provide exceptional staining sensitivity and specificity in immunohistochemical and in situ hybridization assays.