The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Jan. 29, 2010
Ralf Hoffmann, Grosspoesna, DE;
Daniel Knappe, Leipzig, DE;
Anna Klara Brigitte Hansen, Gehrden, DE;
Ralf Hoffmann, Grosspoesna, DE;
Daniel Knappe, Leipzig, DE;
Anna Klara Brigitte Hansen, Gehrden, DE;
AMP-Therapeutics GmbH, Leipzig, DE;
Abstract
The invention relates to a peptide or peptide derivative having the general formula: Sub-X-DK-P-P-Y-L-P-R-P-X-P-P-R-X-I-P/Y-N-N-X-Sub, wherein Xis a non-polar, hydrophobic group or a positively charged group, Dis asparagine or glutamine, K, X, and Xare positively charged groups, Xis a positively charged group, proline, or a proline derivative; Land Iare non-polar, hydrophobic groups, Yand Yare tyrosine, Rand Rare arginine, Nand Nare asparagine or glutamine, P, P, P, P, P, P, and Pare proline, hydroxyproline, or derivatives thereof, wherein possibly one or two of the groups selected from D, P, P, P, P, P, P, P, and Yare replaced by an arbitrary group and/or Pand Rare exchanged, Subis the free or modified N-terminus, and Subis the free or modified C-terminus. The invention further relates to the use of the peptides and peptide derivatives in medicine, as an antibiotic, in a disinfectant or cleaning agent, as a preservative or in a packaging material, in pharmaceutical research, or in a screening method.