The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Jun. 24, 2010
Laura Cook Blumberg, Lincoln, MA (US);
Julius F. Remenar, Framingham, MA (US);
Örn Almarsson, Shrewsbury, MA (US);
Tarek A. Zeidan, Watertown, MA (US);
Laura Cook Blumberg, Lincoln, MA (US);
Julius F. Remenar, Framingham, MA (US);
Örn Almarsson, Shrewsbury, MA (US);
Tarek A. Zeidan, Watertown, MA (US);
Alkermes Pharma Ireland Limited, Dublin, IE;
Abstract
The invention provides a method of sustained delivery of a lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug by administering to a patient an effective amount of a prodrug compound of the invention wherein upon administration to the patient, release of the parent drug from the prodrug is sustained release. Prodrug compounds suitable for use in the methods of the invention are labile conjugates of parent drugs that are derivatized through carbonyl linked prodrug moieties. The prodrug compounds of the invention can be used to treat any condition for which the lactam, imide, amide, sulfonamide, carbamate or urea containing parent drug is useful as a treatment.