The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2014

Filed:

Sep. 22, 2009
Applicants:

Carl Berthelette, Laval, CA;

Michael Boyd, Saint-Lazare, CA;

Jason Burch, Redwood City, CA (US);

Claude Dufresne, Dollard-des-Ormeaux, CA;

Julie Farand, Jersey City, NJ (US);

Yongxin Han, Kirkland, CA;

Claudio F. Sturino, Ile-Bizard, CA;

Inventors:

Carl Berthelette, Laval, CA;

Michael Boyd, Saint-Lazare, CA;

Jason Burch, Redwood City, CA (US);

Claude Dufresne, Dollard-des-Ormeaux, CA;

Julie Farand, Jersey City, NJ (US);

Yongxin Han, Kirkland, CA;

Claudio F. Sturino, Ile-Bizard, CA;

Assignee:

Merck Sharp & Dohme Corp., Rahway, NJ (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/437 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention is directed to β-carboline sulphonylurea derivatives as EP4 receptor antagonists useful for the treatment of EP4 mediated diseases or conditions, such as acute and chronic pain, inflammation, osteoarthritis, and rheumatoid arthritis. Pharmaceutical compositions and methods of use are also included.


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