The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2014

Filed:

Dec. 19, 2011
Applicants:

Ivan Cornella Taracido, Somerville, MA (US);

Edmund Martin Harrington, Plymouth, MA (US);

Ayako Honda, Quincy, MA (US);

Erin Keaney, Belmont, MA (US);

Inventors:

Ivan Cornella Taracido, Somerville, MA (US);

Edmund Martin Harrington, Plymouth, MA (US);

Ayako Honda, Quincy, MA (US);

Erin Keaney, Belmont, MA (US);

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/505 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention includes novel methods of treating a disease or disorder characterized by hyperactivity of Vps34, and compound as Vps34 inhibitors; particularly compounds of Formula I or a pharmaceutically acceptable salt thereof, as well as methods of treating a disease, disorder, or syndrome associated with Vps34 inhibition, particularly hyperproliferative diseases. The present invention also includes pharmaceutical compositions including compounds of formula I and pharmaceutically acceptable salts thereof.


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