The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Apr. 01, 2014

Filed:

May. 29, 2012
Applicants:

Naohiro Takemoto, Mishima-gun, JP;

Kenji Murata, Mishima-gun, JP;

Norihito Murayama, Minato-ku, JP;

Chikaomi Yamada, Mishima-gun, JP;

Inventors:

Naohiro Takemoto, Mishima-gun, JP;

Kenji Murata, Mishima-gun, JP;

Norihito Murayama, Minato-ku, JP;

Chikaomi Yamada, Mishima-gun, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 43/54 (2006.01); A61K 31/505 (2006.01); C07D 239/02 (2006.01);
U.S. Cl.
CPC ...
Abstract

Compounds of Formula (I) promote axonal outgrowth angiogenesis and can therefore be used to reduce central nerve injuries such as head injury and spinal cord injury, cerebral infarction, ischemic heart diseases, peripheral arterial occlusive diseases, or after-effects of these diseases. in which Nx group is preferably a 6-membered aromatic ring containing two nitrogen atoms; R, Rand Rare each independently a hydrogen atom, an alkyl group, or an amino group; E is an oxygen atom or an —NRgroup (wherein Ris an alkyl group or the like); n is an integer of of 0 to 5; X and Y are each a connected bond, a cycloalkyl group, or —CO—; and Q is a hydrogen atom or a phenyl group.


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