The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Sep. 16, 2010
Hong-hsing Liu, Santa Clara, CA (US);
Gary Allen Peltz, Redwood City, CA (US);
Guochun Liao, Belmont, CA (US);
Timothy Alan Garrow, Mahomet, IL (US);
Hong-Hsing Liu, Santa Clara, CA (US);
Gary Allen Peltz, Redwood City, CA (US);
Guochun Liao, Belmont, CA (US);
Timothy Alan Garrow, Mahomet, IL (US);
The Board of Trustees of The University of Illinois, Urbana, IL (US);
The Board of Trustees of The Leland Stanford Junior University, Palo Alto, CA (US);
Abstract
The present disclosure relates generally to a pharmaceutical compositions and methods of reducing acetaminophen-induced liver toxicity. The disclosure includes pharmaceutical compositions including acetaminophen and one or more components selected from S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof. The disclosure also relates to methods of reducing acetaminophen-induced liver toxicity in a subject by administering or co-administering one or more of S-adenosylhomocysteine (SAH), S-methylmethionine (SMM), or a pharmaceutically acceptable salt thereof, with acetaminophen to a subject.