The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Apr. 01, 2014
Filed:
Feb. 14, 2011
Applicants:
Donald W. Kufe, Wellesley, MA (US);
Surender Kharbanda, Natick, MA (US);
Inventors:
Donald W. Kufe, Wellesley, MA (US);
Surender Kharbanda, Natick, MA (US);
Assignees:
Dana-Farber Cancer Institute, Inc., Boston, MA (US);
Genus Oncology, LLC., Chicago, IL (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/00 (2006.01); A61P 35/00 (2006.01); A61K 9/127 (2006.01); A61K 38/16 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention is directed to improved compositions for cellular delivery of peptides. Using segments of only 3-5 positively-charged residues, one can effectively transfer peptides, including therapeutic peptides, into cells. Also provided are modified peptides such as those include stapled and cyclized peptide technology, as well as peptoids/peptidomimetics.