The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2014
Filed:
Aug. 01, 2012
Chu-biao Xue, Hockessin, DE (US);
Genfeng Cao, Bear, DE (US);
Taisheng Huang, Wilmington, DE (US);
Lihua Chen, Boothwyn, PA (US);
KE Zhang, Wilmington, DE (US);
Anlai Wang, Wilmington, DE (US);
David J. Meloni, Bear, DE (US);
Rajan Anand, Wilmington, DE (US);
Joseph Glenn, Mount Royal, NJ (US);
Brian W. Metcalf, Moraga, CA (US);
Chu-Biao Xue, Hockessin, DE (US);
Genfeng Cao, Bear, DE (US);
Taisheng Huang, Wilmington, DE (US);
Lihua Chen, Boothwyn, PA (US);
Ke Zhang, Wilmington, DE (US);
Anlai Wang, Wilmington, DE (US);
David J. Meloni, Bear, DE (US);
Rajan Anand, Wilmington, DE (US);
Joseph Glenn, Mount Royal, NJ (US);
Brian W. Metcalf, Moraga, CA (US);
Incyte Corporation, Wilmington, DE (US);
Abstract
The present invention relates to compounds of Formula I: wherein variable substituents are defined herein, that modulate the activity of or bind to chemokine receptors such as CCR5. In some embodiments, the compounds of the invention are selective for CCR5. The compounds can be used, for example, to treat diseases associated with chemokine receptor expression or activity such as inflammatory diseases, immune diseases and viral infections.