The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2014

Filed:

Feb. 25, 2011
Applicants:

Mark R. Player, Phoenixville, PA (US);

Raul Calvo, Royersford, PA (US);

Jinsheng Chen, Exton, PA (US);

Sanath Meegalla, Garnet Valley, PA (US);

Daniel Parks, Downington, PA (US);

William Parsons, Belle Mead, NJ (US);

Scott Ballentine, Landsale, PA (US);

Shawn Branum, Easton, PA (US);

Inventors:

Mark R. Player, Phoenixville, PA (US);

Raul Calvo, Royersford, PA (US);

Jinsheng Chen, Exton, PA (US);

Sanath Meegalla, Garnet Valley, PA (US);

Daniel Parks, Downington, PA (US);

William Parsons, Belle Mead, NJ (US);

Scott Ballentine, Landsale, PA (US);

Shawn Branum, Easton, PA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01); A61K 31/5377 (2006.01); A61K 31/437 (2006.01); A61K 31/52 (2006.01); A61K 31/4985 (2006.01); A61P 29/00 (2006.01); C07D 487/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention is directed to substituted aza-bicyclic imidazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by TRP M8, including for example, inflammatory pain, inflammatory hyperalgesia, inflammatory hypersensitivity condition, neuropathic pain, neuropathic cold allodynia, inflammatory somatic hyperalgesia, inflammatory visceral hyperalgesia, cardiovascular disease aggravated by cold and pulmonary disease aggravated by cold.


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