The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2014

Filed:

Oct. 07, 2008
Applicants:

Lutz Reichmann, Cambridge, GB;

Peter Kristensen, Tranbjerg, DK;

Jean-luc Jestin, Paris, FR;

Gregory Paul Winter, Cambridge, GB;

Inventors:

Lutz Reichmann, Cambridge, GB;

Peter Kristensen, Tranbjerg, DK;

Jean-Luc Jestin, Paris, FR;

Gregory Paul Winter, Cambridge, GB;

Assignee:

Domantis Limited, Brentford, Middlesex, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C40B 30/06 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns a method for the selection of a virus comprising the steps of: (a) providing a virus encoding and displaying a fusion polypeptide, said fusion polypeptide comprising a heterologous polypeptide inserted into the sequence of a viral coat protein polypeptide, wherein said virus comprises a cleavable site located within a displayed polypeptide; (b) exposing the virus to a cleaving agent; (c) propagating the virus comprising intact fusion protein.


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