The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2014
Filed:
Jun. 26, 2009
Felix Olasagasti, Santa Cruz, CA (US);
Kate Lieberman, Santa Cruz, CA (US);
Seico Benner, Santa Cruz, CA (US);
Mark A. Akeson, Santa Cruz, CA (US);
Felix Olasagasti, Santa Cruz, CA (US);
Kate Lieberman, Santa Cruz, CA (US);
Seico Benner, Santa Cruz, CA (US);
Mark A. Akeson, Santa Cruz, CA (US);
The Regents of the University of California, Oakland, CA (US);
Abstract
The invention herein disclosed provides for devices and methods that can detect and control an individual polymer in a mixture is acted upon by another compound, for example, an enzyme, in a nanopore in the absence of requiring a terminating nucleotide. The devices and methods are also used to determine rapidly (˜>50 Hz) the nucleotide base sequence of a polynucleotide under feedback control or using signals generated by the interactions between the polynucleotide and the nanopore. The invention is of particular use in the fields of drug discovery, molecular biology, structural biology, cell biology, molecular switches, molecular circuits, and molecular computational devices, and the manufacture thereof.