The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2014

Filed:

Jan. 27, 2012
Applicants:

Benzhong Tang, Hong Kong, CN;

Yuning Hong, Hong Kong, CN;

Sijie Chen, Hong Kong, CN;

Ryan Tsz Kin Kwok, Hong Kong, CN;

Inventors:

Benzhong Tang, Hong Kong, CN;

Yuning Hong, Hong Kong, CN;

Sijie Chen, Hong Kong, CN;

Ryan Tsz Kin Kwok, Hong Kong, CN;

Assignee:
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 (2006.01); G01N 33/53 (2006.01); G01N 33/543 (2006.01);
U.S. Cl.
CPC ...
Abstract

The presently described subject matter is directed to a water-soluble conjugated polyene compound and the derivatives thereof that exhibit aggregation induced emission, as well as any water dispersible, fluorescent, polymeric microparticles, nanoparticles, and/or pharmaceutical composition comprising the water-soluble conjugated polyene compound and/or the derivatives thereof. Also provided are methods of making and using the compound, derivatives and particles of the presently described subject matter. The presently described water-soluble conjugated polyene compound are useful as bioprobes for the detection of biomacromolecules, in the manufacture of sensors, in monitoring and retarding formation of amyloid protein fibril in vitro and in vivo, and in developing anti-cancer drugs.


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