The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 25, 2014
Filed:
Feb. 19, 2009
Ravindra K. Pandey, Williamsville, NY (US);
Chao Liu, Barcelona, ES;
Mahabeer Dobhal, Jaipur, IN;
William Potter, Amherst, NY (US);
Janet Morgan, Buffalo, NY (US);
Stephanie Pincus, Buffalo, NY (US);
Ravindra K. Pandey, Williamsville, NY (US);
Chao Liu, Barcelona, ES;
Mahabeer Dobhal, Jaipur, IN;
William Potter, Amherst, NY (US);
Janet Morgan, Buffalo, NY (US);
Allan Oseroff, Buffalo, NY (US);
Health Research, Inc., Buffalo, NY (US);
Abstract
Tetrapyrrolic photosensitizers and imaging agent compounds having A, B, C, and D rings and having a reduced B ring and an oxidized D ring. The compounds preferably have a purity of at least 95 percent and preferably have a fused system connected at an unsaturated carbon atom of the C ring nearest the D ring and at the unsaturated carbon atom between the C and D rings. The invention also includes a method of making the compounds at over 95 percent yield by starting with a B and D ring oxidized tetrapyrollic compound and dissolving it in a halogenated hydrocarbon solvent and treating it with sufficient nitroalkane solution of FeCl6HO to oxidize the D ring and separating the resulting organic layer and drying.