The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 25, 2014

Filed:

Jan. 25, 2010
Applicants:

Geoff C. Gerhardt, Millbury, MA (US);

Joseph A. Luongo, Walpole, MA (US);

Inventors:

Geoff C. Gerhardt, Millbury, MA (US);

Joseph A. Luongo, Walpole, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B01D 15/08 (2006.01);
U.S. Cl.
CPC ...
Abstract

A method and apparatus for monitoring and controlling nano-scale flow rate of fluid in the operating flow path of a HPLC system provide fluid flow without relying on complex calibration routines to compensate for solvent composition gradients typically used in HPLC. The apparatus and method are used to correct the flow output of a typical, analytical-scale (0.1-5 mL/min) HPLC pump to enable accurate and precise flow delivery at capillary (<0.1 mL/min) and nano-scale (<1 μL/min) HPLC flow rates.


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