The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
May. 26, 2010
Applicants:
Gerhard Kretzschmar, Frankfurt am Main, DE;
Volker Kraft, Frankfurt am Main, DE;
Thomas Olpp, Frankfurt am Main, DE;
Kai Rossen, Frankfurt am Main, DE;
Inventors:
Gerhard Kretzschmar, Frankfurt am Main, DE;
Volker Kraft, Frankfurt am Main, DE;
Thomas Olpp, Frankfurt am Main, DE;
Kai Rossen, Frankfurt am Main, DE;
Assignee:
SANOFI, Paris, FR;
Primary Examiner:
Int. Cl.
CPC ...
C07D 307/80 (2006.01);
U.S. Cl.
CPC ...
Abstract
A process for the production of 2-alkyl-3-aroyl-5-nitrobenzofurans by acylation of 2-(2-hydroxy-5-nitrophenyl)-1-aryl-ethanones and subsequent treatment of the esters with combinations of bases and proton acids or Lewis acids. This process can be used for the production of Dronedarone. Furthermore, novel intermediates for the manufacture of Dronedarone are provided.