The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Apr. 20, 2012
Brian Luisi, Mansfield, MA (US);
Sneha Ghanshyam Arekar, Brighton, MA (US);
Adriana Costache, Cambridge, MA (US);
Kirk Raymond Dinehart, Holliston, MA (US);
Steven C. Johnston, Litchfield, NH (US);
Bobbianna J. Neubert-langille, Sudbury, MA (US);
Brian Luisi, Mansfield, MA (US);
Sneha Ghanshyam Arekar, Brighton, MA (US);
Adriana Costache, Cambridge, MA (US);
Kirk Raymond Dinehart, Holliston, MA (US);
Steven C. Johnston, Litchfield, NH (US);
Bobbianna J. Neubert-Langille, Sudbury, MA (US);
Vertex Pharmaceuticals Incorporated, Boston, MA (US);
Abstract
The present invention relates to crystalline solvate forms of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide (Compound 1) and methods for their preparation. The present invention further relates to pharmaceutical compositions comprising the crystalline solvate forms, as well as methods of treatment therewith.