The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Jan. 08, 2009
Applicants:
Frank Sainsbury, Norfolk, GB;
George Peter Lomonossoff, Norfolk, GB;
Inventors:
Frank Sainsbury, Norfolk, GB;
George Peter Lomonossoff, Norfolk, GB;
Assignee:
Plant Bioscience Limited, Norwich, Norfolk, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 15/83 (2006.01); C12N 15/33 (2006.01); C12N 15/113 (2010.01); A01H 5/00 (2006.01);
U.S. Cl.
CPC ...
Abstract
The inventions is based on an expression enhancer sequence derived from the RNA-2 genome segment of a bipartite RNA virus, in which a target initiation site in the RNA-2 genome segment has been mutated. Deletion of appropriate start codons upstream of the main RNA2 translation initiation can greatly increase in foreign protein accumulation without the need for viral replication. Also provided are methods, vectors and systems, including the 'hyper-translatable' Cowpea Mosaic Virus ('CPMV-HT') based protein expression system.