The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Jul. 08, 2011
Applicants:
Zhiyong Qiu, Los Angeles, CA (US);
Adrian Ion Bot, Valencia, CA (US);
Inventors:
Zhiyong Qiu, Los Angeles, CA (US);
Adrian Ion Bot, Valencia, CA (US);
Assignee:
Mankind Corporation, Valencia, CA (US);
Primary Examiner:
Int. Cl.
CPC ...
C07H 21/02 (2006.01);
U.S. Cl.
CPC ...
Abstract
The present invention provides a method of treating cancer by providing to a subject in need thereof an immunogenic composition comprising a nucleic acid construct encoding a polypeptide comprising CTL epitopes PSMAand PRAME, or a cross-reactive analogue. In embodiments of the present invention there is provided methods and compositions for inducing, entraining, and/or amplifying the immune response to MHC class-I restricted epitopes of carcinoma antigens to generate an effective anti-cancer immune response.