The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Mar. 09, 2011
Kamal Ahmed, Hyderabad, IN;
Suresh Paidakula, Hyderabad, IN;
Ashwini Kumar Banala, Hyderabad, IN;
Adla Malla Reddy, Hyderabad, IN;
Papagiri Venkat Reddy, Hyderabad, IN;
Kamal Ahmed, Hyderabad, IN;
Suresh Paidakula, Hyderabad, IN;
Ashwini Kumar Banala, Hyderabad, IN;
Adla Malla Reddy, Hyderabad, IN;
Papagiri Venkat Reddy, Hyderabad, IN;
Council of Scientific & Industrial Research, New Delhi, IN;
Abstract
The present invention provides compounds of general formula (3) as useful potential antitumour agents against human cancer cell lines. The present invention further provides a process for the synthesis of 4β-acrylamidopodophyllotoxin congeners of general formula (3), wherein R and R1 are an aryl group and R is selected from 3,4,5-trimethoxyphenyl or 2-methoxy phenyl and R1 is selected from the group consisting of 4-hydroxy-3-methoxyphenyl, 3-hydroxy-4-methoxyphenyl, 4-fluoro-3-methoxyphenyl, 3-fluoro-4-methoxyphenyl, 2-fluoro-5-methoxyphenyl, 2-fluoro-4-methoxyphenyl, 4-hydroxy-3-nitrophenyl, 4-methoxy-3-nitrophenyl, 4-nitrophenyl, 3-nitrophenyl, 2-nitro phenyl, 4-methoxyphenyl, 3-methoxyphenyl and 4-hydroxyphenyl.