The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2014

Filed:

Nov. 17, 2008
Applicants:

Shawn Maddaford, Mississauga, CA;

Jailall Ramnauth, Brampton, CA;

Suman Rakhit, Mississauga, CA;

Joanne Patman, Mississauga, CA;

Paul Renton, Toronto, CA;

Subhash C. Annedi, Mississauga, CA;

John S. Andrews, Mississauga, CA;

Gabriela Mladenova, Thornhill, CA;

Inventors:

Shawn Maddaford, Mississauga, CA;

Jailall Ramnauth, Brampton, CA;

Suman Rakhit, Mississauga, CA;

Joanne Patman, Mississauga, CA;

Paul Renton, Toronto, CA;

Subhash C. Annedi, Mississauga, CA;

John S. Andrews, Mississauga, CA;

Gabriela Mladenova, Thornhill, CA;

Assignee:

NeurAxon, Inc., Mississauga, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/535 (2006.01); A61K 31/44 (2006.01); A61K 31/445 (2006.01); A61K 31/40 (2006.01); C07D 401/00 (2006.01); C07D 411/00 (2006.01); C07D 209/04 (2006.01);
U.S. Cl.
CPC ...
Abstract

The invention features methods of treating visceral pain or a condition in a mammal caused by the action of nitric oxide synthase (NOS) or by the action of serotonin 5HT1D/1B receptors, by administering to a patient in need thereof a therapeutically effective amount of an indole compound of Formula (I), or a pharmaceutically acceptable salt or prodrug thereof. The methods of the invention may further comprise the administration of additional therapeutic agent. The invention also features new compounds of Formula (I), pharmaceutical compositions thereof, and methods of resolving enantiomeric mixtures.


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