The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 18, 2014

Filed:

Jun. 13, 2007
Applicants:

Matthew S. Bogyo, Redwood City, CA (US);

Amir M. Sadaghiani, Palo Alto, CA (US);

Steven Verhelst, Palo Alto, CA (US);

Inventors:

Matthew S. Bogyo, Redwood City, CA (US);

Amir M. Sadaghiani, Palo Alto, CA (US);

Steven Verhelst, Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 303/48 (2006.01); C07D 401/12 (2006.01); A61K 31/5377 (2006.01); A61K 31/336 (2006.01); A61K 31/40 (2006.01); A61K 31/4427 (2006.01); A61K 31/4523 (2006.01); A61K 31/403 (2006.01); A61K 31/496 (2006.01); A61P 37/06 (2006.01); A61P 35/00 (2006.01); A61P 19/02 (2006.01); A61P 21/00 (2006.01); A61P 25/00 (2006.01); A61P 11/00 (2006.01); A61P 1/00 (2006.01); A61P 31/00 (2006.01); A61P 29/00 (2006.01); C07D 303/02 (2006.01); C07D 213/02 (2006.01); C07D 209/02 (2006.01); C07D 221/00 (2006.01); C07D 207/00 (2006.01); C07D 295/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

Provided herein are novel epoxide inhibitors of cysteine proteases, compositions comprising the epoxide inhibitors, and packaged pharmaceuticals. Also provided are methods of inhibiting a papain-family cysteine protease and methods of treating or preventing a disease by administering a composition containing an epoxide inhibitor of the invention. The compositions may be administered in combination with another therapeutic agent.


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