The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Apr. 25, 2005
Shinji Nakade, Tsukuba, JP;
Tomoyuki Shouno, Mishima-gun, JP;
Takao Shimizu, Bunkyo-ku, JP;
Takehiko Yokomizo, Koshigaya, JP;
Yoshiko Iizuka, Bunkyo-ku, JP;
Shinji Nakade, Tsukuba, JP;
Tomoyuki Shouno, Mishima-gun, JP;
Takao Shimizu, Bunkyo-ku, JP;
Takehiko Yokomizo, Koshigaya, JP;
Yoshiko Iizuka, Bunkyo-ku, JP;
Ono Pharmaceutical Co., Ltd., Osaka, JP;
Abstract
[PROBLEM] The compound that selectively binds to BLT2 and the preventive and/or therapeutic drug for BLT2-mediated disease such as skin disease are needed. [MEANS FOR SOLVING THE PROBLEMS] The present invention provides the compound with BLT2 binding activity, salt thereof, solvate thereof or prodrug thereof. Since the compound with BLT2 binding activity, particularly the compound represented by the formula (I), salt thereof, solvate thereof or prodrug thereof (symbols in formula have the same meanings as specification.) have BLT2 binding activity, it is useful for prevention and/or therapy of BLT2 mediated diseases, e.g., dermatosis, intestinal disease, HIV infection, acquired immunodeficiency syndrome, rejection to transplant, transplant rejection, graft-versus-host disease, autoimmune disease, allergic disease, inflammation, infection, ulcers, lymphoma, malignant tumor, leucaemia, arterial sclerosis, hepatitis, hepatic cirrhosis or cancer, etc.