The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Dec. 16, 2008
Brian H. Bird, Woodland, CA (US);
Cesar G. Albarino, Atlanta, GA (US);
Stuart T. Nichol, Atlanta, GA (US);
Thomas G. Ksiazek, Lilburn, GA (US);
Brian H. Bird, Woodland, CA (US);
Cesar G. Albarino, Atlanta, GA (US);
Stuart T. Nichol, Atlanta, GA (US);
Thomas G. Ksiazek, Lilburn, GA (US);
Abstract
Described herein are recombinant RVF viruses comprising deletions in one or more viral virulence genes, such as NSs and NSm. The recombinant RVF viruses, generated using a plasmid-based reverse genetics system, can be used as vaccines to prevent infection of RVF virus in livestock and humans. As described herein, the recombinant RVF viruses grow to high titers, provide protective immunity following a single injection and allow for the differentiation between vaccinated animals and animals infected with wild-type RVF virus.