The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Dec. 07, 2006
Laurence Tatiana Rimsky, Kapellen, BE;
Inky Paul Madeleine DE Baere, Temse, BE;
Bart Anna Julien Maes, Rumst, BE;
Marie-pierre T. M. M. G. DE Bethune, Everberg, BE;
Guenter Kraus, Sint-Katelijne-Waver, BE;
Elisa Mokany, Kirrawee, AU;
Alison Velyian Todd, Glebe, AU;
Laurence Tatiana Rimsky, Kapellen, BE;
Inky Paul Madeleine De Baere, Temse, BE;
Bart Anna Julien Maes, Rumst, BE;
Marie-Pierre T. M. M. G. De Bethune, Everberg, BE;
Guenter Kraus, Sint-Katelijne-Waver, BE;
Elisa Mokany, Kirrawee, AU;
Alison Velyian Todd, Glebe, AU;
Speedx Pty Ltd., Eveleigh, AU;
Janssen R&D Ireland, Little Island, Co. Cork, IE;
Abstract
The present invention relates to methods and means for the evaluation of HIV replicative capacity in a given environment. In particular, the invention provides a growth competition assay that can determine relative viral fitness using a recombinant tagged HIV-1 virus system. The methods rely on plasmid vectors, amplicons, primers and probes, and the generation of replication-competent viruses therefrom. Said methods and materials may find use in multiple fields including diagnostics, drug screening, pharmacogenetics and drug development.