The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 18, 2014
Filed:
Sep. 12, 2011
Robert A. Brodsky, Brooklandville, MD (US);
Richard J. Jones, Baltimore, MD (US);
Francis E. O'donnell, Jr., Town and Country, MO (US);
Susan Bonitz, Flemington, NJ (US);
Carlos Santos, Tampa, FL (US);
Robert A. Brodsky, Brooklandville, MD (US);
Richard J. Jones, Baltimore, MD (US);
Francis E. O'Donnell, Jr., Town and Country, MO (US);
Susan Bonitz, Flemington, NJ (US);
Carlos Santos, Tampa, FL (US);
The Johns Hopkins University, Baltimore, MD (US);
Accentia Biopharmaceuticals, Inc., Tampa, FL (US);
Abstract
The present invention relates to methods of treating a cancer and in particular, a B-cell derived cancer, using a lymphocytotoxic but hematopoeitic cell sparing high-dose pulsed amount of an oxazaphosphorine drug in combination with immune therapeutics such as, for example, an autologous idiotypic vaccine and monoclonal antibodies that selectively bind B-cell specific antigens.