The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Mar. 21, 2012
Jih-heng LI, Taipei, TW;
A-mei Huang, Kaohsiung, TW;
Chung-yi Chen, Kaohsiung, TW;
Pei-jung Lien, Kaohsiung, TW;
Chiung-hui Liu, Nantou County, TW;
Jih-Heng Li, Taipei, TW;
A-Mei Huang, Kaohsiung, TW;
Chung-Yi Chen, Kaohsiung, TW;
Pei-Jung Lien, Kaohsiung, TW;
Chiung-Hui Liu, Nantou County, TW;
Kaohsiung Medical University, , TW;
Abstract
What is disclosed in the invention is a preparation method of a supercriticalextract, which is made from the material, the dried stem of. The extract is obtained by extractingwhich is pulverized as particles with supercritical carbon dioxide fluid. Theextract or its active ingredient, subamolide A, can be used to inhibit the growth of human urothelial carcinoma cell lines. In addition, theextract (or subamolide A) is able to synergistically inhibit the growth of human urothelial carcinoma cell lines with cisplatin (CDDP) or gemcitabine (Gem). Therefore, theextract (or subamolide A) can be an anticancer drug alone, or forms a pharmaceutical composition with CDDP (or Gem) to treat with cancers in respect of urinary system.