The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Mar. 11, 2014

Filed:

Sep. 18, 2006
Applicants:

Bill Baker, Tampa, FL (US);

Thushara Diyabalanage, Tampa, FL (US);

James B. Mcclintock, Birmingham, AL (US);

Charles D. Amsler, Pelham, AL (US);

Inventors:

Bill Baker, Tampa, FL (US);

Thushara Diyabalanage, Tampa, FL (US);

James B. McClintock, Birmingham, AL (US);

Charles D. Amsler, Pelham, AL (US);

Assignees:

University of South Florida, Tampa, FL (US);

The UAB Research Foundation, Birmingham, AL (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 313/00 (2006.01); C12N 9/99 (2006.01); A61K 31/335 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
Abstract

The present invention concerns groups of compounds derived from tunicates of thespecies, as well as to pharmaceutical compositions comprising these compounds, and uses thereof. Extracts from tunicates show selective toxicity against several different cancer cell lines in the NCI 60 cell line panel. These compounds are useful in the effective treatment of cancers, particularly malignant melanomas, colon cancer, and renal cancer cell lines.


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