The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
May. 23, 2013
Hetero Research Foundation, Andhra Pradesh, IN;
Bandi Parthasaradhi Reddy, Hyderabad, IN;
Kura Rathnakar Reddy, Hyderabad, IN;
Rapolu Raji Reddy, Hyderabad, IN;
Dasari Muralidhara Reddy, Hyderabad, IN;
Thungathurthy Srinivas Rao, Hyderabad, IN;
Hetero Drugs Limited, , IN;
Abstract
The present invention provides a novel and stable hydrated form of erlotinib free base, and a process for its preparation thereof. The present invention also provides a process for preparation of erlotinib hydrochloride crystalline polymorph a substantially free of polymorph B. The present invention further relates to erlotinib hydrochloride crystalline particles having mean particle size (D) ranging from about 4 μm to 15 μm and 90 volume-% of the particles (D) ranging from about 14 μm to 30 μm, to the methods for the manufacture of said crystalline particles, and to pharmaceutical compositions comprising said crystalline particles.