The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Mar. 11, 2014
Filed:
Jan. 27, 2009
Applicants:
Sridhar Mani, Riverdale, NY (US);
Bhaskar C. Das, West Nyack, NY (US);
Inventors:
Sridhar Mani, Riverdale, NY (US);
Bhaskar C. Das, West Nyack, NY (US);
Assignee:
Albert Einstein College of Medicine of Yeshiva University, Bronx, NY (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/496 (2006.01); C07D 317/22 (2006.01);
U.S. Cl.
CPC ...
Abstract
The application discloses ketoconazole derivatives that are antagonists of the human pregnane X receptor (PXR), methods of preparing the derivatives, uses of the derivatives with drug therapy, and methods of inhibiting tumor cell proliferation and multidrug resistance using inhibitors of PXR.